Nummer 2-hits 401 t/m 500
| Nr. | eerste | wk | |
| 401 | 29/1/2000 | 2 | Show me the meaning of being lonely - Backstreet Boys |
| 402 | 26/2/2000 | 3 | Shalala lala - Vengaboys |
| 403 | 1/4/2000 | 3 | Maria Maria - Santana featuring the Product G&B |
| 404 | 24/6/2000 | 3 | Let's get loud - Jennifer Lopez |
| 405 | 28/10/2000 | 1 | Walk on water - Milk Inc. |
| XX | 11/11/2000 | 1 | Walk on water - Milk Inc. |
| 406 | 18/11/2000 | 1 | Shape of my heart - Backstreet Boys |
| 407 | 25/11/2000 | 4 | Independent women part I (Charlie's Angels OST) - Destiny's Child |
| 408 | 23/12/2000 | 3 | Stan - Eminem featuring Dido |
| 409 | 10/2/2001 | 7 | You - Judith |
| 410 | 31/3/2001 | 2 | Played-a-live (The bongo song) - Safri Duo |
| 411 | 14/4/2001 | 3 | Survivor - Destiny's Child |
| 412 | 5/5/2001 | 3 | Moi... Lolita - Alizée |
| 413 | 26/5/2001 | 2 | I was made to love you - Sita & Bart |
| 414 | 16/6/2001 | 2 | We come 1 - Faithless |
| 415 | 30/6/2001 | 5 | Lady Marmalade - Christina Aguilera / Lil' Kim / Mýa / P!NK |
| 416 | 4/8/2001 | 2 | Ain't it funny - J.Lo |
| 417 | 1/9/2001 | 1 | Let me blow ya mind - Eve featuring Gwen Stefani |
| XX | 15/9/2001 | 2 | Let me blow ya mind - Eve featuring Gwen Stefani |
| 418 | 3/11/2001 | 1 | Overcome - Live |
| 419 | 22/12/2001 | 1 | ResuRection - PPK |
| 420 | 23/2/2002 | 2 | Get the party started - P!NK |
| 421 | 9/3/2002 | 2 | The world's greatest - R. Kelly |
| 422 | 23/3/2002 | 1 | Adiós nonino - Carel Kraayenhof / Concertgebouw Kamerorkest (Concertmeester Johan Kracht) / Nederlands Kamerkoor / Ed Spanjaard |
| 423 | 4/5/2002 | 4 | 4 my people - Missy "Misdemeanor" Elliott |
| 424 | 1/6/2002 | 1 | If tomorrow never comes - Ronan Keating |
| 425 | 29/6/2002 | 1 | Désenchantée - Kate Ryan |
| 426 | 6/7/2002 | 3 | A little less conversation - Elvis vs JXL |
| XX | 17/8/2002 | 1 | A little less conversation - Elvis vs JXL |
| 427 | 24/8/2002 | 2 | Because the night - Jan Wayne |
| 428 | 7/9/2002 | 2 | Tu es foutu - In-Grid |
| 429 | 21/9/2002 | 2 | Complicated - Avril Lavigne |
| 430 | 5/10/2002 | 1 | Round round - Sugababes |
| 431 | 12/10/2002 | 5 | All the things she said - t.A.T.u. |
| 432 | 16/11/2002 | 6 | Dirrty - Christina Aguilera featuring Redman |
| 433 | 8/2/2003 | 2 | Nu flow - Big Brovaz |
| 434 | 22/2/2003 | 1 | Beautiful - Christina Aguilera |
| 435 | 1/3/2003 | 1 | Alles - Tooske Breugem & Bastiaan Ragas |
| 436 | 12/4/2003 | 1 | In da club - 50 Cent |
| 437 | 19/4/2003 | 1 | Make luv - Room 5 featuring Oliver Cheatham |
| XX | 26/4/2003 | 1 | In da club - 50 Cent |
| 438 | 3/5/2003 | 2 | Clocks - Coldplay |
| 439 | 17/5/2003 | 1 | She - Di-rect |
| 440 | 24/5/2003 | 1 | Rock your body - Justin Timberlake |
| 441 | 31/5/2003 | 2 | Ik wou dat ik jou was - Veldhuis & Kemper |
| XX | 21/6/2003 | 3 | Ik wou dat ik jou was - Veldhuis & Kemper |
| 442 | 12/7/2003 | 4 | Crazy in love - Beyoncé featuring Jay-Z |
| 443 | 9/8/2003 | 1 | This love is real - Jim |
| 444 | 30/8/2003 | 2 | Ch!pz in black (Who you gonna call) - Ch!pz |
| XX | 20/9/2003 | 1 | Ch!pz in black (Who you gonna call) - Ch!pz |
| 445 | 4/10/2003 | 4 | Traffic - Tiësto |
| 446 | 1/11/2003 | 1 | Hole in the head - Sugababes |
| XX | 22/11/2003 | 2 | Hole in the head - Sugababes |
| 447 | 7/2/2004 | 1 | Shut up - the Black Eyed Peas |
| 448 | 10/4/2004 | 2 | Left outside alone - Anastacia |
| 449 | 15/5/2004 | 1 | My band - D12 |
| 450 | 21/8/2004 | 1 | Sick and tired - Anastacia |
| 451 | 28/8/2004 | 2 | Push up - Freestylers |
| 452 | 11/9/2004 | 2 | My place - Nelly |
| 453 | 2/10/2004 | 1 | Viben - K-Liber |
| 454 | 20/11/2004 | 2 | Vertigo - U2 |
| 455 | 18/12/2004 | 1 | Girl - Anouk |
| XX | 29/1/2005 | 1 | Girl - Anouk |
| 456 | 19/2/2005 | 1 | De kleine krokodil - Snappie |
| 457 | 26/2/2005 | 1 | Get right - Jennifer Lopez |
| XX | 5/3/2005 | 2 | De kleine krokodil - Snappie |
| 458 | 19/3/2005 | 2 | Lost - Anouk |
| 459 | 23/4/2005 | 2 | Leipe mocro flavour - Ali B, Brayce & Yes-R |
| 460 | 4/6/2005 | 1 | Don't phunk with my heart - the Black Eyed Peas |
| 461 | 23/7/2005 | 1 | Kuma he - K3 |
| 462 | 30/7/2005 | 4 | We belong together - Mariah Carey |
| 463 | 27/8/2005 | 1 | Vaag en stil - André Hazes |
| 464 | 24/9/2005 | 2 | Don't cha - the Pussycat Dolls featuring Busta Rhymes |
| 465 | 26/11/2005 | 4 | Love generation - Bob Sinclar featuring Gary Pine |
| 466 | 7/1/2006 | 1 | Nine million bicycles - Katie Melua |
| 467 | 14/1/2006 | 2 | Stickwitu - the Pussycat Dolls |
| 468 | 11/2/2006 | 2 | Aanzoek zonder ringen - Blřf met Kodo |
| 469 | 4/3/2006 | 3 | Sorry - Madonna |
| 470 | 1/4/2006 | 1 | No worries - Simon Webbe |
| 471 | 8/4/2006 | 2 | Beep - the Pussycat Dolls featuring Will.I.Am |
| 472 | 22/4/2006 | 1 | La camisa negra - Juanes |
| 473 | 29/4/2006 | 2 | One - Mary J. Blige and U2 |
| XX | 10/6/2006 | 1 | La camisa negra - Juanes |
| 474 | 17/6/2006 | 2 | Wij houden van Oranje - Ali B featuring André Hazes |
| 475 | 14/10/2006 | 2 | You give me something - James Morrison |
| 476 | 28/10/2006 | 4 | I don't feel like dancin' - Scissor Sisters |
| 477 | 16/12/2006 | 2 | Hurt - Christina Aguilera |
| 478 | 3/3/2007 | 1 | A good thing - Di-rect |
| 479 | 10/3/2007 | 2 | She's Madonna - Robbie Williams with Pet Shop Boys |
| 480 | 24/3/2007 | 1 | Maak me gek - Gerard Joling |
| 481 | 31/3/2007 | 1 | Confessions - XYP |
| 482 | 14/4/2007 | 2 | In the dark - Tiësto featuring Christian Burns |
| 483 | 28/4/2007 | 4 | Say it right - Nelly Furtado |
| 484 | 2/6/2007 | 6 | Umbrella - Rihanna featuring Jay-Z |
| 485 | 14/7/2007 | 4 | Do you know? (The ping pong song) - Enrique Iglesias |
| 486 | 27/10/2007 | 4 | Alles is liefde - Blřf |
| 487 | 8/12/2007 | 1 | De speelgoeddief - Coole Piet |
| 488 | 29/1/2008 | 4 | Father & friend - Alain Clark |
| XX | 8/3/2008 | 1 | Father & friend - Alain Clark |
| 489 | 29/3/2008 | 3 | Betekenis - Jeroen van der Boom |
| 490 | 26/7/2008 | 2 | Stilte in de storm - Jan Smit |
| 491 | 9/8/2008 | 1 | Ella elle l'a - Kate Ryan |
| 492 | 16/8/2008 | 2 | All summer long - Kid Rock |
| 493 | 11/10/2008 | 1 | Sweet about me - Gabriella Cilmi |
| 494 | 18/10/2008 | 5 | Infinity 2008 - Guru Josh Project |
| 495 | 27/1/2009 | 2 | Human - the Killers |
| 496 | 11/4/2009 | 4 | Sweet goodbyes - Krezip |
| 497 | 4/7/2009 | 5 | When love takes over - David Guetta featuring Kelly Rowland |
| 498 | 24/10/2009 | 1 | Hot - Inna |
| 499 | 31/10/2009 | 3 | MaMaSé! - K3 |
| 500 | 26/12/2009 | Tik tok - Ke$ha |